TUBB3 antibody (AA 436-450)

Catalog No. ABIN781811

The Mouse Monoclonal anti-TUBB3 antibody has been validated for WB, IF and IHC (p). It is suitable to detect TUBB3 in samples from Human, Mouse, Rat and Cow.

Quick Overview for TUBB3 antibody (AA 436-450) (ABIN781811)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human, Mouse, Rat, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: N-a

Product Details anti-TUBB3 Antibody

Binding Specificity: AA 436-450

Sequence: C-MYEDDEEESE AQGPK

Specificity: Recognizes Human neuronal specific beta-3 Tubulin.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat and Bovine.
Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogen: synthetic peptide KLH coupled corresponding to amino acids 436-450 of neuronal specific beta-3 Tubulin. Epitope: EAQGPK

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris-glycine, 0.11 M Sodium Chloride, pH 7.4, 0.05 % Sodium Azide and 30 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3 / TUBB4

Background: The beta-3 Tubulin isotype is present dominantly in cells of neuronal origin and it is one of the earliest marker of neuronal differentiation. Class III beta-tubulin, is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The neuron-associated class III beta-tubulin isotype is most abundant in cells of neuronal origin but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

Gene ID: 10381

NCBI Accession: NP_001184110

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase